Mon, Jan 27, 2003: BSI releases version 1.2 of PEAKS automated de novo sequencing software

Waterloo, January 27, 2003. Bioinformatics Solutions Inc. (BSI) today announced the version 1.2 release of PEAKS, BSI's automated de novo MS/MS peptide sequence software. PEAKS accepts MS/MS data input in Micromass,(.PKL), Sequest (.DTA) and Mascot Generic Format (.MGF) to provide fast, accurate auto de novo and semi-manual sequencing functionality.

PEAKS de novo approach efficiently searches all possible combinations of amino acids for a given MS/MS spectrum. As PEAKS does not use a database searching methodology, sequence prediction accuracy is not limited by the diversity of any given database - providing great results for unknown peptides.

This latest release includes new features to define and search for post-translational modifications (PTMs). The PEAKS Residue List Manager provides a modification library of 26 common PTMs and a facility for defining custom PTMs. Modified and unmodified residues can be grouped into residue lists to provide quick access to frequently used search sets.

More information and a demo download version of PEAKS can be found at the BSI website http://www.bioinformaticssolutions.com/.

Bioinformatics Solutions Inc. is headquartered in Waterloo, Ontario. BSI continues to develop advanced algorithms and innovative software, providing innovative solutions for drug discovery. In addition to PEAKS, BSI has developed PatternHunter, a desktop homology software up to 400 times faster than Blast at the same sensitivity and PROSPECT, an award-winning 3-D protein structure prediction software.